Medicated lozenges and pastilles

Lozenges and pastilles are commonly used OTC treatments for sore throats. Their main use is to soothe and moisten the throat. Based on evidence and experience, NICE states that “people may wish to try self care with medicated lozenges (containing a local anaesthetic, a NSAID or an antiseptic agent) to help reduce pain in acute sore throat, but should be told that the benefit is likely to be small”.

NICE found no evidence on non-medicated lozenges, mouthwashes or on local anaesthetic mouth sprays (without an antiseptic). Lozenges may persist longer in the throat than sprays or gargles, so may be more effective for symptom relief.

Lozenges containing cetylpyridinium chloride have been shown to have some antibacterial action. Local anaesthetic lozenges will numb the tongue and throat and can help to ease soreness and pain. Benzocaine can cause sensitisation and such reactions have sometimes been reported.